PUBLICATIONS
2024
FOXR2 targets LHX6+/DLX+ neural lineages to drive CNS neuroblastoma
Jessa S, De Cola A, Chandarana B, McNicholas M, Hebert S, Ptack A, Faury D, Tsai JW, Korshunov A, Phoenix TN, Ellezam B, Jones DTW, Taylor MD, Bandopadhayay P, Pathania M, Jabado N, Kleinman CL. 2024. Cancer Research.
How to set up your new lab space
Coppola M, Tsai JW. 2024. Nature.
2023
Cell lineage analysis with somatic mutations reveals late divergence of neuronal cell types and cortical areas on human cerebral cortex
Kim SN, Viswanadham VV, Doan RN, Dou Y, Bizzotto S, Khoshkoo S, Huang AY, Yeh R, Chhouk B, Truong A, Chappell KM, Beaudin M, Barton AR, Akula SK, Rento L, Lodato M, Ganz J, Szeto RA, Li P, Tsai JW, Hill RS, Park PJ, Walsh CA. 2023. bioxRiv.
Integrated response analysis of pediatric low-grade gliomas during and after targeted therapy treatment
Tsai JW, Choi JJ, Ouaalam H, Murillo EA, Yeo KK, Vogelzang J, Sousa C, Woods JK, Ligon KL, Warfield SK, Bandopadhayay P, Cooney TM. 2023. Neuro-Oncology Advances.
BH3 mimetics targeting BCL-XL impact the senescent compartment of pilocytic astrocytoma
Selt F, Sigaud R, Valinciute G, Sievers P, Zaman J, Alcon C, Schmid S, Peterziel H, Tsai JW, Guiho R, Martínez-Barbera JP, Pusch S, Deng J, Zhai Y, van Tilburg CM, Schuhman MU, El Damaty A, Bandopadhayay P, Herold-Mende C, von Deimling A, Pfister SM, Montero J, Capper D, Oehme I, Sahm F, Jones DTW, Witt O, Milde T.
2023. Neuro-Oncology.
ALK Amplification and Rearrangements Are Recurrent Targetable Events in Congenital and Adult Glioblastoma
Blandin, AF, Giglio R, Graham MS, Garcia G, Malinowski S, Woods JK, Ramkissoon S, Ramkissoon L, Dubois F, Schoolcraft K, Tsai JW, Wang D, Jones R, Vogelzang J, Pelton K, Becker S, Watkinson F, Sinai C, Cohen EF, Booker MA, Tolstorukov MY, Haemels V, Goumnerova L, Wright K, Kieran M, Fehnel K, Reardon D, Tauziède-Espariat A, Lulla R, Carcamo B, Chaleff S, Charest A, De Smet F, Ligon AH, Dubuc A, Pages M, Varlet P, Wen PY, Alexander BM, Chi S, Alexandrescu S, Kittler R, Bachoo R, Bandopadhayay P, Beroukhim R, Ligon KL. 2023. Clinical Cancer Research.
2022
FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits
Tsai JW, Cejas P, Wang DK, Patel S, Wu DW, Arounleut P, Wei X, Zhou N, Syamala S, Dubois FPB, Crane A, Pelton K, Vogelzang J, Sousa C, Baguette A, Chen X, Condurat AL, Dixon-Clarke SE, Zhou KN, Lu SD, Gonzalez EM, Chacon MS, Digiacomo JJ, Kumbhani R, Novikov D, Hunter J, Tsoli M, Ziegler DS, Dirksen U, Jager N, Balasubramanian GP, Kramm CM, Nathrath M, Bielack S, Baker SJ, Zhang J, McFarland JM, Getz G, Aguet F, Jabado N, Witt O, Pfister SM, Ligon KL, Hovestadt V, Kleinman CL, Long H, Jones DTW, Bandopadhayay P, Phoenix TN. 2022. Cancer Research.
Liu APY, Northcott PA. Pursuing FOXR2-Driven Oncogenesis. 2022. Cancer Research.
Somatic mutations in single human cardiomyocytes reveal age-associated DNA damage and widespread oxidative genotoxicity
Choudhury S, Huang AY, Kim J, Zhou Z, Morillo K, Maury EA, Tsai JW, Miller MB, Lodato MA, Araten S, Hilal N, Lee EA, Chen MH, Walsh CA.
2022. Nature Aging.
Upfront molecular targeted therapy for the treatment of BRAF-mutant pediatric high-grade glioma
Rosenberg T, Yeo KK, Mauguen A, Alexandrescu S, Prabhu SP, Tsai JW, Malinowski S, Joshirao M, Parikh K, Farouk Sait S, Rosenblum MK, Benhamida JK, Michaiel G, Tran HN, Dahiya S, Kachurak K, Friedman GK, Krystal JI, Huang MA, Margol AS, Wright KD, Aguilera D, MacDonald TJ, Chi SN, Karajannis MA. 2022. Neuro-Oncology.
Structural variants shape driver combinations and outcomes in pediatric high-grade glioma
Dubois FPB, Shapira O, Greenwald NF, Zack T, Wala J, Tsai JW, Crane A, Baguette A, Hadjadj D, Harutyunyan AS, Kumar KH, Blattner-Johnson M, Vogelzang J, Sousa C, Kang KS, Sinai C, Wang DK, Khadka P, Lewis K, Nguyen L, Malkin H, Ho P, O'Rourke R, Zhang S, Gold R, Deng D, Serrano J, Snuderl M, Jones C, Wright KD, Chi SN, Grill J, Kleinman CL, Goumnerova LC, Jabado N, Jones DTW, Kieran MW, Ligon KL, Beroukhim R, Bandopadhayay P. 2022. Nature Cancer.
SAi: an experimental incubator for informal science learning initiatives
Muindi FJ, Holesovsky CM, Tsai JW. 2022. Trends in Cell Biology.
2021
Outcomes after first relapse of childhood intracranial ependymoma
Tsai JW, Manoharan N, Alexandrescu S, Zimmerman MA, Scully J, Chordas C, Clymer J, Wright KD, Filbin M, Ullrich NJ, Marcus KJ, Haas-Kogan D, Chi SN, Bandopadhayay P, Yeo KK. 2021. Pediatric Blood & Cancer.
Learning to listen: A plea to our profession
Umaretiya PJ, Tsai JW. 2021. Pediatric Blood & Cancer.
Dissecting and modeling photic and melanopsin effects to predict sleep disturbances induced by irregular light exposure in mice
Hubbard J, Kobayashi Frisk M, Ruppert E, Tsai JW, Fuchs F, Robin-Choteau L, Husse J, Calvel L, Eichele G, Franken P, Bourgin P. 2021. PNAS.
Attitudes Toward Implicit Bias and Implicit Bias Training Among Pediatric Residency Program Directors: A National Survey
Tsai JW, Michelson CD. 2021. The Journal of Pediatrics.
2009-2020
Addressing implicit bias in pediatric hematology-oncology
Tsai JW, Kesselheim JC. 2020. Pediatric Blood & Cancer.
Human Narratives in Science: The Power of Storytelling
Muindi FJ, Ramachandran L, Tsai JW. 2020. Trends in Molecular Medicine.
Transcriptional Feedback Links Lipid Synthesis to Synaptic Vesicle Pools in Drosophila photoreceptors
Tsai JW, Kostyleva R, Chen PL, Rivas-Serna IM, Clandinin MT, Meinertzhagen IA, Clandinin TR. 2019. Neuron.
Bazan NG, Gordon WC. Learning from the Fly Photoreceptor on How Synapses Integrate Gene Expression to Sustain Retina and Brain Function. 2019. Neuron.
Rectify biased interpretation of science history.
Kabeer A, Tsai JW. 2018. Nature.
Optimizing the utility of the individual development plan for trainees in the biosciences
Tsai JW, Vanderford NL, Muindi F. 2018. Nature Biotechnology.
Can You See the Gorilla?
Tsai JW. 2018. Academic Pediatrics.
Saving Ourselves, Our Patients, and Our Profession: Making the Case for Narrative Competence in Pediatrics
Hester CN, Tsai JW. 2018. Academic Pediatrics.
Making Conscious the Unconscious
Tsai JW. 2017. JAMA Pediatrics.
Processing Death
Tsai JW. 2017. JAMA Oncology.
Family Matters
Tsai JW. 2016. JAMA Pediatrics.
Towards sustaining a culture of mental health and wellness for trainees in the biosciences
Tsai JW, Muindi F. 2016. Nature Biotechnology.
The M.D.-Ph.D. double agent
Tsai JW. 2015. Science.
Melanopsin as a sleep modulator: circadian gating of the direct effects of light on sleep and altered sleep homeostasis in Opn4(-/-) mice
Tsai JW, Hannibal J, Hagiwara G, Colas D, Ruppert E, Ruby NF, Heller HC, Franken P, Bourgin P. 2009. PLOS Biology.
Dijk D-J, Archer SN. Light, Sleep, and Circadian Rhythms: Together Again. 2009. PLOS Biology.